Jason Chen of Gizmodo has had the chance to play around with the Palm Pre and he has posted a detailed review of the Palm Pre.

Here are the positives of Plam Pre as mentioned in the review:

The Palm Pre has the best Multitouch functionality compared to other phones in the market. It is also more accurate and responsive than the iPhone's.
The Screen is bright, crisp and as good as the iPhone's.
The Web OS is the best feature of the Palm Pre. It provides a number of useful features such as Universal Search, Notification bar, Gesture Area and Synergy.
Multi-Tasking works quite well on the Pre and the device doesn't slow down even if you have many applicatios running simultaneously.
The Pre Multimedia player is as good as the iPhone's and supports more video codecs than the iphone.
Battery life is good enough for a day's computing tasks.

Here are the negatives as mentioned in the review:

The build quality of the Palm Pre is not that impressive and platicky. Another major flaw is that the bottom edge of the phone is quite sharp. May be the next versions of the Palm Pre will come with a better build quality.
The Home Screen only allows five shortcuts.
The keys on the QWERTY keyboard are too small, plasticky and lacking feedback.
Camera is not that impressive and similar to the iPhone's or G1's.
Contact Dialing isn't user-friendly and relies on Universal Search or Speed Dialing.
The Pre Application Launcher requires a lot of scrolling to find your desired App.

Jump over to Gizmodo to read the complete review.